Schedule

Logon | 8:30 am - 8:50 am

Opening remarks:  Trevor Boram, Organizing Committee Chair | 8:50 am - 9:00 am

Scientific Session 1: Frontiers in Bioinformatics | Moderator: Mackenzie Chapman

Opening Speaker: Dr. Genki Terashi; Purdue University, Biological Sciences| 9:00 am - 9:40 am

VESPER: Global and Local Cryo-EM Map Alignment and Database Search Using Local Density Vectors 

Xiao Wang; Purdue University, Computer Science | 9:40 am - 10:00 am

Emap2sec+: Detecting Protein and DNA/RNA Structures in Cryo-EM Maps of Intermediate Resolution Using Deep Learning

Barrett Davis; Purdue University, Biomedical Engineering | 10:00 am - 10:20 am

Computational Model of PDZ-Binding Competition and AMPA Receptor Insertion in the Postsynaptic Density(PSD)

Daipayan Sarkar; Purdue University, Biological Sciences | 10:20 am - 10:40 am

Mem-LZeRD: Modeling transmembrane protein interactions using topological and biophysical principles

Coffee Break | 10:40 am - 10:50 am

Keynote Lecture

Keynote Speaker Introduction by Trevor Boram | 10:55 am - 11:00 am

Keynote Speaker: Dr. Doug Lauffenburger; MIT, Department of Biological Engineering | 11:00 am - 12:00 pm

Hijacked by Covid: Antibody-Centric Immune Systems Analysis, Intensely Applied

Scientific Session 2: Enzymology Across Life | Moderator: Sebastian Kenny

Opening Speaker: Dr. Angeline Lyon; Purdue University, Chemistry | 1:00 pm - 1:40 pm

A Structure-Based Approach to Understanding Phospholipase C Function

Chelsea St. Germain; Purdue University, Chemistry | 1:40 pm - 2:00 pm

Characterization of the binding site of the zinc metalloprotease, Ste24

Karthik Srinivasan; Purdue University, Biological Sciences | 2:00 pm - 2:20 pm

Characterizing Fabs for the isolation of the TOC Complex

Tapiwa Chiura; Saint Louis University, Chemistry | 2:20 pm - 2:40 pm

Resonance Raman unveils a tilted configuration for the cyano adducts of human heme oxygenase

Coffee Break | 2:40 - 3:00 pm 

Scientific Session 3: Investigating Human Disease with Novel Techniques | Moderator: Ari Cardillo

Opening Speaker: Dr. Shalini Low-Nam, Purdue University, Chemistry and Physics & Astronomy | 3:00 pm - 3:40 pm

Physical mechanisms of T cell signaling and activation at the single molecule, single cell level

Fan Xu; Purdue University, Biomedical Engineering | 3:40 pm - 4:00 pm

Three dimensional super-resolution imaging in whole-cell and tissue specimens

Muriel Eaton; Purdue University, MCMP | 4:00 pm - 4:20 pm

Substantial reduction of Scn2a expression renders behavioral abnormalities in mice indicative of autism spectrum disorder

Marco Hadisurya; Purdue University, Biochemistry | 4:20 pm - 4:40 pm 

Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define diagnostic and prognostic biosignatures for Parkinson's Disease

BIOPHYSICAL SOCIETY NETWORKING/SOCIAL | 4:45 pm - 5:45 pm

Facilitator: Sebastian Kenny

Logon | 8:30 am - 8:50 am

Scientific session 4: Fighting Bacterial Pathogens through Biophysics | Moderator: Evan Billings

Opening Speaker: Dr. Nicholas Noinaj; Purdue University, Biological Sciences | 9:00 am - 9:40 am

The β-barrel Assembly Machinery in Motion

Shalini Iyer; Purdue University, Chemistry | 9:40 am - 10:00 am

Modulation of host signaling by two syntenic genes of Legionella pneumophila

Ravi Yadav; Purdue University, Biological Sciences | 10:00 am - 10:20 am

Structural insight into dual function of Neisserial lactoferrin binding protein B

Vatsal Purohit; Purdue University, Biological Sciences | 10:20 am - 10:40 am

Ionic Inhibition utilized to develop a pH-dependent reaction triggering method in PmHMGR crystals

Coffee Break and Lighting Talk Set-up | 10:40 am - 10:55 am

Scientific Session 5: Design and Characterization of Peptide Analogs | Moderator: Kristos Negron

Opening Speaker: Dr. Daniel Flaherty; Purdue University, MCMP | 1:00 pm - 1:40 pm

Optimization and structural studies of inhibitors for bacterial carbonic anhydrases

Nicolas Varas; Indiana University, Biochemistry & Molecular Biology | 1:40 pm - 2:00 pm

A new fibrillation-resistant glucagon analogue

Austin Cool; The Ohio State University, Chemistry & Biochemistry | 2:00 pm - 2:20 pm

Computational Methods Elucidate Consequences of Mutations and Post-Translational Modifications on Troponin I Effective Concentration to Troponin C

Christine Muli; Purdue University, MCMP | 2:20 - 2:40 pm

Binding Site Discovery of a Peptidomimetic Probe on Proteasome Ubiquitin Receptor, Rpn-13

Coffee Break | 2:40 - 3:00 pm 

Scientific Session 6: Innovative Biophysical Methodologies | Moderator: Clint Gabel

Opening Speaker: Dr. Fang Huang; Purdue University, Biomedical Engineering | 3:00 pm - 3:40 pm

Revealing Subcellular Structures with Live-cell and 3D Fluorescence Nanoscopy

Andrew DeMarco; Purdue University, Biochemistry | 3:40 pm - 4:00 pm

Phosphatase and Kinase Substrate Specificity Profiling with Pool Synthetic Peptides and Mass Spectrometry

Ryan Benke; Purdue University, Biochemistry | 4:00 pm - 4:20 pm

Using Metabolomics and Association Genetics to Map Lesion Mimic Mutants

Soutick Saha; Purdue University, Physics & Astronomy | 4:20 pm - 4:40 pm

Capacity to multitask limits cellular chemotaxis  

Closing Remarks and Award Announcements | 4:40 pm