Schedule

Check-In and Breakfast | 8:00 am - 8:45 am

ARMSTRONG Lobby/Atrium

Opening remarks: Mackenzie Chapman, HG2BG Committee Chair | 8:45 am - 9:00 am

ARMSTRONG 1010

Scientific Session 1: An Eclipse of Proteins

Moderator: Kevin Scrudders, HG2BG Committee

ARMSTRONG 1010

Opening Speaker: Dr. James Geiger; Michigan State University, Dept. of Chemistry | 9:00 am - 9:40 am

The retinal binding protein family: a powerful template for design and discovery

Hui Ma; Purdue University, Weldon School of Biomedical Engineering | 9:40 am - 10:00 am

Protein-protein interaction measurement using particle diffusometry in a low-volume microfluidic chip

Owen Tyoe; University of Cincinnati, Dept. of Physics | 10:00 am - 10:20 am

α-Synuclein - lipid membraneinteraction and the binding mechanismof the N-terminal region

Elisabeth Garland-Kuntz; Purdue University, Dept. of Chemistry | 10:20 am - 10:40 am

Structural Insights into Phospholipase Cε 

Coffee Break | 10:40 am - 11:00 am

ARMSTRONG Lobby/Atrium

Keynote Lecture | Dr. Janet Smith; University of Michigan Medical School | 11:00 am - 12:00 pm

Two Molecular Systems for Human Defense against Viral Pathogens

Martha K. Ludwig Distinguished University Professor 

Depts. of Biological Chemistry & Biophysics

LUNCH | 12:00 pm - 1:00 pm

ARMSTRONG Lobby/Atrium

Scientific Session 2: Macromolecular Milky Way

Moderator: Emily David, HG2BG Committee

ARMSTRONG 1010

Opening Speaker: Dr. Betsy Parkinson; Purdue University, Dept. of Chemistry | 1:00 pm - 1:40 pm

Synthetic Natural Product Inspired Cyclic Peptidesfor Discovery of Bioactive Natural Products and Biocatalysts

Trevor Boram; Purdue University, Dept. of Biochemistry | 1:40 pm - 2:00 pm

Probing the catalytic interactions of ketosynthases using near-natural substrate analogs 

Samadhi C. Kulathunga; Purdue University, Dept. of Chemistry | 2:00 pm - 2:20 pm

In-vitro characterization and inhibitionstudies of Sulfotransferase 1A1 as a potential therapeutic target for structure-based design of drugs toovercome drug resistance in breast cancer.

Yu-Chen Yen; Purdue University, Dept. of Biological Sciences | 2:20 pm - 2:40 pm

 Cryo-EM structures of ACKR3 reveal molecular mechanisms forbiasedsignaling and promiscuit

Coffee Break and Group Photo | 2:40 pm - 3:00 pm

ARMSTRONG Lobby/Atrium

Workshop Session | 3:00 pm - 5:00 pm

Mastering your 'Aims' - ARMSTRONG 1109 

Insights into AlphaFold - ARMSTRONG 1103 

New Instrumentation in Revolutionizing Structural Biology - ARMSTRONG 1028 

Making figures and movies in PyMOL and Chimera/X - AMRSTRONG 1021

BIOPHYSICAL SOCIETY NETWORKING/SOCIAL | 5:00 pm - 5:30 pm

Facilitator: Mackenzie Chapman

ARMSTRONG CAFE

Check-In and Breakfast| 8:00 am - 8:45 am

ARMSTRONG Lobby/Atrium

Scientific Session 3: Black Hole of Biochemistry

Moderator: Ryan Imhoff, HG2BG Committee

ARMSTRONG 1010

Opening Speaker: Dr. Jonathan P. Schlebach; Indiana University, Dept. of Chemistry | 9:00 am - 9:40 am

Pharmacological Profiling of Cystic FibrosisVariantsby Deep Mutational Scanning

Chun-Liang Chen; Purdue University, Dept. of Biological Sciences | 9:40 am - 10:00 am

Structural and mechanistic basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ 

Kaushik Muralidharan; Purdue University, Dept. of Biological Sciences | 10:00 am - 10:20 am

Understanding the molecular mechanisms of PLCε regulation

Haley R. Harrington; Indiana. University, Dept. of Chemistry  | 10:20 am - 10:40 am

Determining the Constraints of -1 Programmed Ribosomal Frameshifting in Alphaviruses 

Coffee Break | 10:40 am - 11:00 am

Poster Session--Group 1 |  11:00 am - 12:00 pm

Purdue Memorial Union, South Ballroom

LUNCH | 12:00 pm - 1:00 pm

Purdue Memorial Union, South Ballroom

Poster Session--Group 2 |  1:00 pm - 2:00 pm

Purdue Memorial Union, South Ballroom

Scientific Session 4: A Constellation of Methods

Moderator: Clint Gabel, HG2BG Committee

ARMSTRONG 1010

Opening Speaker: Dr. Lauren Ann Metskas; Purdue University, Depts. of Biological Sciences & Chemistry | 2:00 pm - 2:40 pm

Structures in situ: solving a Rubisco structure and interactions inside intact carboxysomes 

Tunde Aderinwale; Purdue University, Dept. of Computer Science | 2:40 pm - 3:00 pm

Real-Time Structure Search and Structure Classification for AlphaFold Protein Models

Matthew Clark; Purdue University, Dept. of Chemistry | 3:00 pm - 3:20 pm

Imaging and controlling chemical processes in live cells with real-time precision opto-control (RPOC)

Sajad Shiekh; Kent State University, Dept. of Physics | 3:20 pm - 3:40 pm

FRET-PAINT for Studying Long Telomeric DNA Overhangs and their Interactions with Shelterin Proteins

Coffee Break | 3:40 pm - 4:00 pm

ARMSTRONG Lobby/Atrium

Closing Remarks: Dr. Leifu Chang, HG2BG Faculty Mentor | 4:00 pm 

ARMSTRONG 1010

Award Presentation: Mackenzie Chapman, HG2BG Committee Chair | 4:15 pm

ARMSTRONG 1010