Official Program

Nicole M Hjortland

_{(Graduate student in Department of Biological Sciences, Purdue University)}

Decoupling the allosteric activation of ubiquitin specific protease 7 by its ubiquitin-like domains for the development of small molecule inhibitors

Basudev Chowdhury

_{(Post-doctoral scholar in Medicinal Chemistry and Molecular Pharmacology, Purdue University}

PBRM1 regulates the transcription of genes linked to cell adhesion in renal cell carcinoma

Shankar Thangamani

_{(Graduate student in Department of Comparative Pathobiology, Purdue University)}

Yu-Chen Yen

_{(Graduate student in Department of Biological Sciences, Purdue University)}

Structure-based drug design for selective inhibitors against the BACE protein family for the treatment of Alzheimer’s disease and Type II Diabetes

Matthew L. Wohlever

_{(Post-doctoral scholar in Department of Biochemistry and Molecular Biology, University of Chicago)}

Quality control of mitochondrial tail-anchored proteins

Manish Nepal 

_{(Graduate student in Department of Chemistry , Purdue University)}

Promoting metal-assisted hierarchal assembly in coiled coil peptides

Saeed S. Akhand

_{(Graduate Student in Medicinal Chemistry and Molecular Pharmacology, Purdue University)}

Covalent inhibition of FGFR overcomes metastatic resistance to Her2 targeted therapies in breast cancer

Jeremy Bakelar

_{(Post-doctoral scholar in Department of Biological Sciences, Purdue University)}

Structural analysis of the E.coli beta-barrel assembly machinery complex

Nathan Gardner

_{(Graduate student in Medicinal Chemistry and Molecular Pharmacology\PULSe, Purdue University)}

The structure of an E. coli phosphoglycerate mutase intermediate reveals a physical basis for cooperativity between ligand binding and dimerization

Yan Zhang

_{(Post-doctoral scholar in Life Sciences Institute,University of Michigan)}

2.8-angstrom cryo-EM structure of the large ribosomal subunit from the parasite Leishmania

Chao Feng

_{(Graduate student in Medicinal Chemistry and Molecular Pharmacology, Purdue University)}

Jennifer N. Cash

_{(Post-doctoral scholar in Department of Pharmacology, University of Michigan)}

Structural and functional characterization of the metastatic rhoGEF P-Rex1 and its regulation by Ptdins(3,4,5)P3: towards inhibitory small molecule development

Haroon Mohammad

_{(Graduate student in Department of Comparative Pathobiology, Purdue University)}

Gut check: Discovery of phenylthiazole antibiotics effective against vancomycin-resistant Enterococci

Allison Norvil

_{(Graduate student in Dept. of Biochemistry, Purdue University)}

Dnmt3b methylates DNA by a non-cooperative but processive mechanism

Chun-Liang Chen

_{(Graduate student in Department of Biological Sciences, Purdue University)}

Induced fit model of enzyme-substrate recognition: Study of the mevalonate diphosphate decarboxylase from Enterococcus faecalis

Christopher J. Petell

_{(Graduate student in Department of Biochemistry, Purdue University)}

An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiantion

Duy P. Hua

_{(Graduate Student in Medicinal Chemistry and Molecular Pharmacology, Purdue University)}

Unique allosteric mechanism regulating protein-protein interaction through phosphorylation: a case study of the conformational changes in the Syk tandem SH2 protein

Lenna X. Peterson

_{(Graduate student in Department of Biological Sciences, Purdue University)}

IDR-LZerD: structure prediction of disordered protein interactions

Genki Terashi

_{(Visiting scholar in Department of Biological Sciences, Purdue University)}

An automated C tracing from cryo-EM map

Ying Yang

_{(Graduate Student in Medicinal Chemistry and Molecular Pharmacology, Purdue University)}

Dissecting the influence of protein flexibility on the location and thermodynamic profile of explicit water molecules in protein-ligand binding

Devika Sirohi

_{(Graduate student in Department of Biological Sciences, Purdue University)}

The cryo-EM structure of the Zika virus

Haley Hoover

_{(Graduate student in Department of Molecular and Cellular Biochemistry, Indiana University)}

Host post-translational modification of the brome mosaic virus capsid regulates the timing of viral infection

Vidya Mangala Prasad

_{(Post-doctoral scholar in Department of Biological Sciences, Purdue University)}

Organization of rubella virus structural proteins using cryo-electron tomography

Ranjan Sengupta

_{(Post-doctoral scholar in Department of Biological Sciences, Purdue University)}

From sheets to vesicles; alphavirus steals a page out of the organelle biogenesis handbook of the cell