Dr. J. Patrick Loria

Dr. J. Patrick Loria (Faculty Web Page) 

 "Flexibility of proteins is an integral part of their function. This motion can include reorganization of catalytic groups, loop closures, and domain movement, to name a few. The focus of our research is to understand how the dynamic and structural properties of proteins correlate with their function."

"Currently, our interest center on the relationship between active site loop closure in protein tyrosine phosphatases (YopH, PTP1B, and VHR) and their catalytic activity and whether allosteric ligand can modulate loop motions."

-Dr. J. Patrick Loria